MAIN KEGG FILE RESULTS

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName	#Gene	EntrezGene	Statistics
Natural killer cell mediated cytotoxicity	4	7124 8797 3384 80328	C=136;O=4;E=0.18;R=22.65;rawP=3.06e-05;adjP=0.0002
Notch signaling pathway	3	54567 28514 4242	C=47;O=3;E=0.06;R=49.16;rawP=3.23e-05;adjP=0.0002
Glycosphingolipid biosynthesis - lacto and neolacto series	2	2523 84002	C=26;O=2;E=0.03;R=59.24;rawP=0.0005;adjP=0.0018
Cell adhesion molecules (CAMs)	3	90952 7122 3384	C=133;O=3;E=0.17;R=17.37;rawP=0.0007;adjP=0.0019
Apoptosis	2	7124 8797	C=87;O=2;E=0.11;R=17.70;rawP=0.0058;adjP=0.0091
Cytokine-cytokine receptor interaction	3	7124 8797 6376	C=265;O=3;E=0.34;R=8.72;rawP=0.0050;adjP=0.0091
Neuroactive ligand-receptor interaction	3	9002 286530 1901	C=272;O=3;E=0.35;R=8.49;rawP=0.0054;adjP=0.0091
Leukocyte transendothelial migration	2	90952 7122	C=116;O=2;E=0.15;R=13.28;rawP=0.0100;adjP=0.0138
Axon guidance	2	2050 54910	C=129;O=2;E=0.17;R=11.94;rawP=0.0123;adjP=0.0145
Hepatitis C	2	7124 7122	C=134;O=2;E=0.17;R=11.49;rawP=0.0132;adjP=0.0145

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).